What Does indazole structure Mean?
Substitution at R3 by using a halogen or alkoxy group (74f–74i) triggered a slight increase in cellular potency Along with the halide analogs (74g–h) demonstrating greatest the potency from the group. Further optimization led to the invention of 74i–j, with 74k as quite possibly the most Lively compound while in the series (pIC50 = six.77) wi